Research chemicals are substances that have not been thoroughly studied. These substances are called as such because they were mostly discovered in laboratories and have only been examined in low level animal studies and test tube studies. Some of them have already been around for years while some are quite new. There is no adequate research regarding the pharmacology or toxicology of these drugs.
Also, very few people have been reported to use research chemicals. These drugs are not as popular as marijuana or ecstasy. Because they are unknown, the risks associated with them are higher compared to other drugs.
So are research chemicals safe to ingest? The straight answer to this question is no. Although no drug has been categorically characterized as safe, research chemicals may actually be riskier than older drugs that have been thoroughly studied.
Then again, this does not mean that these chemicals are more dangerous than others. They are only considered risky because very little facts are known about them. As mentioned earlier, very few people have been found to use them. Thus, there are not sufficient reports, claims, or data available regarding these drugs. Their side effects and long term effects have not even been determined.
If you take a research chemical, you practically step into the unknown. You do not know what symptoms you may experience. If the drug is working, then that is good news for you. On the contrary, it may produce highly unpleasant side effects. It may even be fatal. Even if the research chemical is similar to a well-known drug in terms of structure, this still does not mean that it is safe to use.